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Confirmed Left Ventricular Systolic Dysfunction (Mod-severe LVSD on echocardiography) 1st Line Beta-blocker Bisoprolol Dose Schedule 1.25mg daily >1 week: if tolerated increase 2.5mg daily >1 week: if tolerated increase 3.75mg daily >1 week: if tolerated increase 5mg daily >4 week: if tolerated increase
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