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In addition to being a marker of increased risk, diastolic dysfunction may also be a direct contributor to the adverse outcomes, perhaps by contributing to the progression of heart failure by limiting cardiac output reserve, accelerating neuroendocrine activation, increasing symptoms of breathlessness, and promoting physical inactivity .How is diastolic dysfunction treated? Treatment for diastolic dysfunction may include: Lifestyle changes: You may work with your provider to improve your habits. You may quit smoking, lower sodium intake or increase aerobic exercise. Your provider may also recommend a cardiac rehabilitation program to help you improve your overall heart .
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Methods and Results— In a multicenter, double-blind, crossover trial, we compared the effects of LV and biventricular (BiV) pacing on exercise tolerance and LV remodeling in patients with an LV ejection fraction ≤35%, QRS ≥120 milliseconds, and symptoms of heart failure. A total of 211 patients were recruited from 11 centers.
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